1 reason why patients don't even take the first step," Ro co-founder and CEO Zachariah Reitano told CNBC in an interview
Temperature is the single most important factor
For many of those secondary uses, patients need to buy them out-of-pocket without the benefit of insurance, as theyre sometimes technically an off-label use
Abnormal uterine bleeding should always be evaluated with a thorough consultation and examination by a gynecologist for an accurate diagnosis and treatment plan as it may be a symptom or sign of a severe illness or condition

Monitor for: Gastrointestinal symptoms: Nausea or vomiting (occurring in approximately 1520% of patients at therapeutic doses per FDA labeling) Abdominal pain or cramping Diarrhea or constipation Loss of appetite or early satiety Bloating or abdominal distension Hypoglycemia indicators (particularly if you take other diabetes medications): Trembling, shakiness, or sweating Rapid heartbeat or palpitations Dizziness, lightheadedness, or confusion Hunger or irritability Headache or blurred vision Injection site reactions: Bruising, swelling, or hematoma formation Persistent pain or tenderness Redness or warmth suggesting inflammation Hardness or nodule formation under the skin Semaglutide's mechanism involves glucose-dependent insulin secretion, meaning hypoglycemia risk is generally low when used as monotherapy
Nutritional guidance matters