partial sequence of human Body Protection Compound Sequence: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH (GEPPPGKPADDAGLV) CAS Number: 137525-51-0 Molecular Formula: C 62 H 98 N 16 O 22 Molecular Weight: 1419.55 g/mol Mechanism (working): modulation of nitric oxide system, VEGFR-2 expression, and growth factor signaling supporting GI, vascular, and connective-tissue repair Regulatory status: not approved by the FDA or EMA TB-500 Compound class: synthetic N-acetylated heptapeptide
These hydrogels form a gel with mechanical properties comparable to native disc tissue within seconds to minutes
By upregulating VEGFR2 signaling, the compound promotes the formation of new blood vessels in damaged tissue a process called angiogenesis
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This bidirectional NO interaction gives this compound an adaptability in biological environments that single-pathway peptides lack, and may contribute to its consistency of effect across diverse tissue types and experimental conditions
Both were ultimately connected to ventilators