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The study with the highest dose found no significant beneficial effect of NAC

doi: 10.1093/bja/aet402 188

Adropin slightly modulates lipolysis, lipogenesis and expression of adipokines but not glucose uptake in rodent adipocytes

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Hence, this autoantibody presence especially targets the autonomic and central nervous systems (503), which may explain the dysautonomia and immune dysregulation present in ME/CFS (58)