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10.1016/j.joca.2009.11.015 45 FuL.HuY.SongM.LiuZ.ZhangW.YuF.-X.et al (2019)

In receptor pharmacology research, tesamorelin acts as a selective full agonist at the pituitary GHRHR, a class B G-protein-coupled receptor

It regulates: Energy homeostasis , complementarily to MC4R but via different pathways Anti-inflammatory effects in macrophages Sebaceous glands (partially) Activation of MC3R contributes to the metabolic and anti-inflammatory effects of Melanotan II, but is less characterized than MC4R

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