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Atropine's effects last for more than a week (7-10 days of mydriasis, & ~2 weeks of cycloplegia) - this is why it is not used for routine retinal exams requiring mydriasis
Outside the US, yes, and it is already happening
Toxicology 340:34
For musculoskeletal applications, injectable is still the preferred route in research protocols
11, e00849e00823
That is why the same medicine class can still be treated differently in practice
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