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doi: 10.3390/ijms20030708 270 CostaVCostaMVideiraRAAndradePBPaiva-MartinsF
Endocrinology (2008) 149(3):133849
Because the meta-analysis included both European and East Asian samples, but the validation set included primarily European samples, we separately constructed the GRS using either the European only or European and East Asian subsets of 1000 Genomes Phase 3 for clumping in PLINK
This alteration of the microbiota may partly explain the variability in GLP-1RA responsiveness and presents opportunities for combination therapy using probiotics or prebiotics to augment therapeutic effectiveness
~20g/day) for 14 days
With no head-to-head data, comparing the two requires stitching together studies that differ in species, model, route, endpoint, and molecule a chain with several weak links
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