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Similar patterns are observed with tirzepatide discontinuation
And Wegovy and Zepbound are for obesity
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10.1016/j.bbrc.2006.08.155
A SURMOUNT-1 post-hoc analysis of 2,542 women, published in Obesity in 2025, found perimenopausal women on tirzepatide lost 23% of body weight against 3% on placebo, almost identical to the premenopausal result
One reason for this is that semaglutide slows gastric emptying and affects appetite and satiety
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