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What works for someone else may not work for you and we plan for that from day one

8 The best medication depends on your personal health profile, cost considerations, tolerance for side effects, and individual response

Common side effects may include: Nausea Constipation Diarrhea Vomiting Reduced appetite Stomach discomfort Heartburn or reflux Fatigue Many side effects are digestive and may improve as the body adjusts

Again, orforglipron is still being studied and in late clinical trials, but heres the expected timeline: Eli Lilly plans to submit it to the FDA in late 2025 for approval for weight loss in adults with a BMI of 30 or higher, or 27 and higher with a related health condition

This dual-agonist medication targets two hormone receptors instead of one, which might help jumpstart progress

Rather than acting as a direct driver of these processes, it is thought to contribute to the signaling environment that guides them