Vitamin B12 deficiency is not the only serious side effect of nitrous oxide use, so recreational users should monitor their health and watch for side effects like frostbite, signs of poisoning, or seizures
While more research is still needed, some preliminary studies have found lipo B12 may support hair follicles and reduce hair shedding when combined with other hair loss treatments like minoxidil.
The two strategies are therefore not substitutes, and they have very different evidence profiles

Cognitive Decline and Neurodegenerative Conditions Cognitive decline and neurodegenerative conditions show substantial preclinical evidence across multiple pathologies: Stroke models: BPC-157 given during reperfusion counteracted neuronal damage and produced full functional recovery in spatial memory, motor coordination, and balance tests Parkinsons models: MPTP-induced models showed reduced motor symptoms (tremor, rigidity, akinesia), protection of nigrostriatal dopaminergic neurons, and near-complete prevention of mortality Multiple sclerosis models: Cuprizone-induced demyelination resulted in significantly less brain damage and reduced clinical abnormalities when BPC-157 was given in drinking water or intragastrically Traumatic brain injury: Falling weight model studies demonstrated reduced hemorrhage, decreased brain lacerations and edema, and improved early outcomes These diverse models share common mechanisms
Keep the needle in place after the plunger bottoms out
But it removes one biochemical stressor that can make existing vulnerabilities worse