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The phase 3 data arrived later and from an unusual source: the REDEFINE 1 trial, which included a cagrilintide 2.4 mg monotherapy arm alongside CagriSema, semaglutide 2.4 mg and placebo across 3,417 adults with obesity or overweight and at least one comorbidity, without type 2 diabetes
Cardiovascular efficacy and safety are currently being assessed in a dedicated outcomes trial
D., & Katki, H
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Cell viability was expressed as percentage of fluorescence intensity relative to untreated controls
The prevalence of sarcopenia increased steeply with age, reaching 31.6% in women and 17.4% in men older than 80 years [46]
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