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Both are likely to require either significant real world observation in off-label use, or some form of RCT with careful observation
WegebergAL,HansenCS,FarmerAD,etal.Liraglutide accelerates colonic transit in people with type 1 diabetes and polyneuropathy: A randomised, double-blind, placebo-controlled trial.United European Gastroenterol J.2020;8(6):695704
It is also higher after periods of extended fasting, intense exercise, or illness
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In clinical practice, drug selection should therefore prioritize factors such as tolerability, safety profile, adherence, cost, and patient preference rather than expecting major differences in cardiovascular efficacy
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