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Clin Microbiol Rev (2009) 22(2):20223
Findings from this study showed that chronic intracerebroventricular (ICV) of leptin, with no spill over in the circulation, improved cardiac function after ischemia/reperfusion injury in male and female rats and that this effect is not transmitted from the brain to the heart by cardiac sympathetic nerves
& Johnson, E
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15 These results support the hypothesis that NAC is capable of crossing the bloodbrain barrier and providing cysteine substrate to CNS cells, thus enhancing GSH synthesis
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