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In further support of the important role of L-glutamate metabolism in meningococcal virulence, gdhA was found to be essential for meningococcal survival in the infant rat model (Sun et al., 2000)

Timblin GA, Tharp KM, Ford B, Winchester JM, Wang J, Zhu S, Khan RI, Louie SK, Iavarone AT, Ten Hoeve J, Nomura DK, Stahl A, Saijo K (2021) Mitohormesis reprogrammes macrophage metabolism to enforce tolerance

Kerksick, C., Willoughby, D

Monitoring Progress Effectively: Rather than relying solely on scale weight, which can be misleading due to muscle preservation and fluid fluctuations, comprehensive progress tracking should include body composition analysis (DEXA scan, bioelectrical impedance, or skinfold measurements), circumference measurements (waist, hips, thighs, arms), progress photos taken in consistent lighting and positioning, and subjective measures like energy levels, appetite patterns, and how clothing fits

The GIP component enhances insulin sensitivity in fat tissue and may promote beneficial fat metabolism, building on the same principle that makes tirzepatide dosing effective

Seim H et al