The safety was preliminarily verified: The acute toxicity test showed that a single subcutaneous injection of AOD 9604 (50 mg/kg) did not cause death or obvious toxic reactions in mice
In AD, GSH depletion impacts microglia function and reduces -amyloid clearance
The study was approved by the Local Ethics Committee at School of Medicine (University of Zagreb, Zagreb, Croatia) and experiments were assessed by observers unaware of the given treatment
Additionally, NNMT inhibition appears to increase expression of GLUT4 transporters, which move glucose from the bloodstream into cells
AOD-9604 AOD-9604 is a synthetic 16-amino acid peptide fragment corresponding to hGH(177-191) with added N-terminal tyrosine, available as a lyophilized powder for laboratory research.
Manufactured exclusively for laboratory and research purposes.