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doi:10.2337/dc25-2041

The key insight is that the belly fat lost during a well-run peptide cycle tends to stay off if the underlying metabolic improvements are maintained through continued nutrition and exercise habits

Other conditions such as thyroid disorders, infections, anxiety, or other medications can also cause similar symptoms

Some people may find they respond better to one drug than others due to these different mechanisms of action

So, a significantly greater number of people on tirzepatide will achieve clinically meaningful weight loss compared to those losing weight without medication

Many people notice feeling fuller longer and fewer cravings