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Overall, these findings demonstrate that this substrate profiling system can both predict and validate physiologically relevant off-target cleavage events, thereby providing critical information for refining protease specificity for intended applications
they are calculated from the absolute risk reduction between two treatment options in a single study, rather than from an absolute measure of clinical effect, and are sensitive to baseline risk, timeframe, and the outcomes considered
LC-MS, liquid chromatography-mass spectrometry
Alopecia areata can cause hair fall in patches
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