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These modified peptides aim to maintain therapeutic benefits while reducing systemic exposure and potential side effects

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eLife 12 , e69779 (2023)

In rats, the reported average was about 3.8 hours after IV dosing and 6.9 hours after oral dosing

A 12-week trial showed more fat loss than placebo, but the difference was small in absolute terms

The tripeptide has a strong natural affinity for copper (II) ions, similar to the copper-transport site on human albumin, and readily forms the stable GHK-Cu complex