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Using the Genotype Tissue Expression (GTEx release v8 18 ) database in lung, we observed that rs3130660-A is associated with increased FLOT1 expression ( P = 2.22 10 16 , Supplementary Fig
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In addition, due to the inability to effectively detoxify CN, a deficiency of such amino acids has also been postulated to reduce a key antioxidant, glutathione, thereby hindering responses to the cyanide exposure-related oxidative stress, however, direct evidence of this mechanism has been scarce 12,13
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