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Activating upstream targets of the GSH system The key upstream target for GSH system modulation is generally considered to be Nrf2, a redox-sensitive regulator

doi: 10.3389/fimmu.2014.00420 65 PeyssonnauxCDattaVCramerTDoedensATheodorakisEAGalloRLet al

After 10 years in leading the medical school, Perlmutter will shift his focus to two initiatives: the launch of his autophagy therapeutics company and, most critically, the launch of the Washington University Development Corporation (DevCo)

For example, 2-propyl-2-pentenoic acid (2-en-VPA), a byproduct of -oxidation, and 2-propyl-4-pentenoic acid (4-en-VPA), a byproduct of -oxidation, have been incriminated in the development of cerebral oedema and in the hepatotoxicity of VPA, respectively [1724]

It plays a vital role in the development and repair of bodily tissues

PMID 21975791