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The studies also had some shortcomings, as some only administered fluoxetine at the end of pregnancy and could not assess the effects of the drug throughout the entire pregnancy period, some did not explore the specific mechanisms of fluoxetine-induced fetal acidosis, hypocalcemia, and altered maternal estradiol metabolism, and some failed to assess the maternal and fetal health status over a long-term follow-up period

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At very high doses, some horses may show reduced feed acceptance due to the strong odor or taste

In preclinical studies , it has demonstrated the ability to reduce inflammatory signaling and support cellular protection