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However, the largest 24-week trial with 536 participants failed to show statistically significant weight loss, which led to development termination
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What the Clinical Evidence Shows What the Clinical Evidence Shows B12 deficiency and metabolic phenotype A 2023 study of children, adolescents, and young adults found low serum B12 was associated with worse metabolic phenotype across the weight spectrum
That's an odds ratio of 6.87, the highest response rate any drug has achieved in a NASH trial to date [5]
worldobesity.org (2025)
transitory exanthema Miscellaneous: Feeling of swelling of entire body B-12 Compliance Injection Dosage and Administration Avoid using the intravenous route
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