PubMed Lukefahr AL, McEvoy S, Alfafara C, Funk JL
Manufacturing Facilities and FDA Oversight Hospira operates manufacturing facilities in the United States, Australia, Italy, India, and several other countries
BNF British National Formulary Chapter 9 Section 1.2 bnf.nice.org.uk/drug/hydrox
doi: 10.3390/cells11162587 25 BjornholmKDPovlsenGKOugaardMEPykeCRakipovskiGTveden-NyborgPet al
The "half-step" approach: Some researchers soften the 2mg to 4mg transition by doing one week at 3mg before moving to 4mg
Common side effects include: Cognitive slowing, including difficulties with memory, concentration, and word-finding Fatigue and drowsiness Dizziness and coordination problems Paraesthesia (tingling sensations, particularly in the hands and feet) Decreased appetite and weight loss Mood changes, including low mood, depression, and irritability More serious risks include: Metabolic acidosis topiramate inhibits carbonic anhydrase, which can reduce blood bicarbonate levels