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Semaglutide works by mimicking a hormone (glucagon-like peptide-1 [GLP-1]) that targets the areas of the brain regulating appetite

Two hormones in particular, GLP-1 and GIP, help regulate hunger signals and insulin response

Anti-nausea medicines (antiemetics) may occasionally be considered, though their routine use alongside investigational medicines should always be discussed with the supervising medical team

This is mainly driven by a high prevalence of type 2 diabetes and obesity in the region

Current medical guidance recommends that GLP-1 medications should not be used during pregnancy