Liraglutide has anti-inflammatory effects on endothelial cells by decreasing activation of NF-kB, inhibiting TNF-alpha, and increasing nitric oxide production (28)
However, safety depends on several factors: injection site rotation to avoid lipodystrophy, adequate hydration (both agents can increase fluid demand), and monitoring of B vitamin status since semaglutide may affect nutrient absorption slightly during rapid weight loss phases
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Low-molecular fraction of wheat protein hydrolysate stimulates glucagon-like peptide-1 secretion in an enteroendocrine L cell line and improves glucose tolerance in rats
Obesity and Metabolism, 12(1), 16-19
Geng RS et al