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2022;119(30):e2119368119

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9 : 3946 Taglialatela G, Angelucci L, Ramacci MT, Werrbach-Perez K, Jackson GR, Perez-Polo JR

This pulsatile pattern is considered more physiologic , closely mirroring how our body naturally releases growth hormone (several pulses mostly during deep sleep each 24 hours)

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65,78,79,80,81,82,83,84,85,86 Thus, at present, non-proliferative and proliferative astrocyte reactivity represent two broad categories that can be readily differentiated and are associated with diverse molecular and functional differences