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Despite these major discoveries, further studies are needed to implement them in current and future spacecraft designs (152), aiming at dose reduction through improvement of structure configuration and development of new materials
Ironsulfur cluster protein CDGSH iron sulfur domain (CISD) 1, a mitochondrial outer membrane protein, regulates VDAC in a redox-dependent manner in cells and closes mitochondrial pores to prevent iron accumulation in the mitochondria [49]
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