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G.CostaA.2003Expression of phosphatidylethanolamine N-methyltransferase in human hepatocellular carcinomas.652(2003),152158,0030-2414 108
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Mientras que su forma oxidada ejerce una accin prooxidante, su forma reducida (GSH o L-Glutatin) est en primera lnea de la defensa celular (2)
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Prescribers considering this formulation should be aware of the patient's overall health status, including any other medications being taken, to avoid potential drug interactions
Clinical experience with PRLX93936 underscores the ceiling for systemic dosing, as a phase I trial was terminated early when patients experienced severe, intolerable toxicity at very low doses (93), revealing an exceptionally narrow therapeutic index
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