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Cells were collected and washed with PBS once, and cellular fluorescence was determined by flow cytometry and data were collected by BD FACSCanto and analyzed with FlowJo V.10.1 software
SARS-CoV-2, Severe acute respiratory syndrome Coronavirus 2
Namely, redox-active metals, like Fe 2+ , react with peroxides generating highly active hydroxyl radicals (R-HO ) that further propagate the peroxidation reaction ( Cysteine, Lipid Peroxides and Ferroptosis Glutathione-Dependent Ferroptosis Since characterization of ferroptosis in 2012, the cysteine-GSH-GPx4 axis is described as essential pathway for its regulation, and thus seen as potential therapeutic target
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It is also indicated for use to manage vitamin B12 deficiency in adult patients with vitamin B12 requirements
Certain medical conditions, such as pernicious anemia, may also mean injections are needed
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