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There is no receptor competition, no shared metabolic bottleneck, and no known interaction that would create problems when running them together

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Following library preparation, paired-end sequencing was performed on the Illumina NovaSeq platform targeting the 16S rRNA V3-V4 region

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Short-term GLP-1R/GCGR dual agonism results in normal insulin secretory capacity during hyperglycemic clamp in DIO mice Having assessed insulin sensitivity using the hyperinsulinemic euglycemic clamp, we next sought to examine the impact of cotadutide on insulin secretory capacity and -cell function in response to hyperglycemia