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En animales e insectos, la glutamato cistena ligasa (GCL) es una enzima heterodimrica compuesta por un catalizador (GCLC) y subunidad moduladora (GCLM)

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Consistent with this mechanism, exendin-4 treatment suppressed the phosphorylation of Foxo-1 in 3T3-L1 adipocytes (Fig 3B, 1st panel)

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