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Lignans from flaxseed, converted to enterolactone (EL) and enterodiol by gut microflora within the intestines, possess weak estrogenic activity that competes with endogenous oestrogens for ER binding causing decreased mitogenic stimulation and lower circulating estrogen concentrations via upregulation of sex hormonebinding globulin (SHBG) (189, 190)
Many expired prescriptions maintain their efficacy, or at least most of it, long after that date
doi: 10.3389/fmicb.2020.00090 74 HanLShuXWangJ
Instead, they function like a well-coordinated team
doi:10.1007/s12325-021-01789-5
It is distinguished from its successors primarily by its pronounced appetite-stimulating effects, the strongest of any GHRP, and its broader hormonal footprint that includes modest elevations in cortisol and prolactin at higher doses
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