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Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes
The common parlance of nutritional gaps is an oversimplification and does not take into account absorption challenges and depletion caused by factors other than lack of dietary consumption
Patients commonly experience weight loss of 10% or more over several months, with full effects often observed within 12 to 24 weeks
A complete blood count (CBC) can also reveal megaloblastic anemia, a hallmark of B12 deficiency
This is further supported by our findings that either inducible Nrf2 deletion or interference of selected Nrf2-induced metabolic genes (e.g., G6pdx or Gclc ) impairs early activation of MuSCs (Figs
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