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When a relationship has been found, it does not appear to be specific to a particular GLP-1/GIP agonist or route of administration (subcutaneous injection vs
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As the dosage is increased, the effects become more pronounced
These diseases may affect more people in todays aging society
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Zabawski Jr EJ, Washak RV, Cohen JB, Cockerell CJ, Brown SM
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(2023) found that GLP-1 receptor agonists reduced the risk of lower limb amputation by 43% compared to sulfonylureas (HR: 0.57, 95% CI: 0.390.84), with the greatest risk reduction observed in long-term users (HR: 0.44, 95% CI: 0.270.72).(26) However, GLP-1 receptor agonists did not significantly impact diabetic foot ulcer incidence (HR: 1.08, 95% CI: 0.871.35)
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