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International Journal of Pharmaceutics 494 , 471478, (2015)
Doses up to 60mg/kg per day produced no observable toxicity
Here we find increased proportion of pro-inflammatory and mesenchymal fibroblast subpopulations and senescent fibroblasts, and enhanced expression of senescence-associated secretory phenotype genes using single-cell RNA sequencing analysis, as well as elevated p16 protein and more -galactosidase-positive cells in keloids
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Pyo HK, et al
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