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Improvements in these markers suggest beneficial effects on glucose metabolism

Moreover, we found that for both CD4 and CD8 CAR T cells, HK and G6PD expression levels showed a significant correlation, further supporting the potentially coupled activity of the two step-limiting rate enzymes of glycolysis and the PPP, respectively (Fig

Through the T-cell receptor (TCR) and CD3 co-receptor complex, T cells recognize antigens presented on MHC class I or II molecules by antigen-presenting cells and initiate downstream effector functions (116)

By donating electrons, it helps stabilize these reactive molecules and may protect against oxidative damage to cells