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NO has also been observed to nitrosylate JNK1 (blocking its autophagy-activating function) (247) and IKK, reducing AMPK phosphorylation while activating mTORC1, leading to autophagy suppression (248, 249)

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doi:10.3390/medsci13020058

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Guidance for industry: Diabetes mellitus evaluating cardiovascular risk in new antidiabetic therapies to treat type 2 diabetes