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Mistretta CM, Kumari A

A strong, temporary reduction in food intake lasting around four hours

Long-term considerations and what to expect after the adjustment period Once you survive the initial adjustment, what comes next

However, the same study also found lower/more attenuated post-prandial responses of GLP-1 and GIP [106], consistent with findings from a subsequent study that found worsening OSA was associated with reduced GLP-1 levels [107]

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For targeted therapeutic support during severe symptom flares or intense detoxification protocols, some functional medicine providers may recommend temporarily increasing the dose to 300 mg or 400 mg per day, though this should always be done under medical supervision