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In light of the amyloid cascade hypothesis considerable research effort has focused on the accumulation of insoluble brain A protein as a basic cause of AD [47,48]

The thousands of anecdotal human reports suggest similar effects to animal studies, but formal human clinical trials remain lacking

Exposure to heat, moisture, or repeated freeze-thaw cycles should be minimized to preserve analytical integrity

At the same time , studies explore how peptide-mediated signaling participates in regulatory processes across different tissue types

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