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As GLP-1 therapy progresses and weight loss occurs, your provider may need to reduce or discontinue some antihypertensive medications to prevent symptomatic low blood pressure, but this decision requires medical supervision and regular blood pressure monitoring

When the condition is suspected or known to occur in a family, genetic testing can be helpful in identifying the specific individuals who have or carry the disorder

[11] [12] The most serious but rare adverse effect is lactic acidosis, which occurs primarily in patients with significant renal impairment, acute illness, or conditions causing tissue hypoxia

You note that patients are mixed on their satisfaction with currently available HS treatments, and these patients often have concurrent conditions

Those taking more of the drug did show more improvement, though

In clinical practice, the addition of BPC-157 has been associated with improved rather than worsened GI tolerance, consistent with BPC-157's known gastroprotective pharmacology