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Early inflammation recruits dendritic cells and macrophages, which present thyroid autoantigensprimarily thyroglobulin (Tg) and thyroid peroxidase (TPO)via MHC class II molecules

That, the article says, is what makes the combination unpredictable

Aqueous solvents such as sterile water or bacteriostatic water are preferred for in vivo rodent studies because they eliminate the confounding variable of DMSO's own biological activity, which includes membrane permeabilization and anti-inflammatory effects

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