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It wasnt until the success of GLP-1 medications for diabetes in 2005 and, later, obesity in 2021 that peptides became a major focus of the pharmaceutical industry, Kates said

In order to determine if compounds showed selective inhibition of TGR compared to human TrxR and GR, the IC 50 values for TGR were compared to those of human TrxR and GR either reported in literature or determined here (Table 4)

Directed evolution of glutathione transferases towards a selective glutathione-binding site and improved oxidative stability

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Guanfacine's mechanism of action in treating prefrontal cortical disorders: Successful translation across species

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