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Under neurotoxic conditions, some astrocytes adopt maladaptive phenotypesreferred to as neurotoxic astrocytesinduced by microglial cytokines, characterized by the loss of supportive functions and secretion of factors that damage neurons
N.SangeethaK.VijayalakshmiK.BarhoumA
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Corning Incorporated) at 37C in a 95% air-5% CO 2 humidified atmosphere for 24 hours in complete medium with or without MSU crystals (1 mg/mL) and with or without the indicated concentrations of -MSH or (CKPV) 2
Butterfield DA (2007) Amyloid -peptide(1-42), oxidative stress, and Alzheimers disease
The inorganic sulfate used for the phase II sulfation pathway is derived from a process called sulfoxidation, which converts those sulfur amino acids (e.g., cysteine and methionine) into the sulfate
