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[ CrossRef ] [ Google scholar ] [ PubMed ] Peled T, Landau E, Prus E, Treves AJ, Fibach E

In a study by Brown et al

Instead: Use copper peptides in a separate routine (AM/PM split) or alternate on different days when using strong exfoliating or resurfacing products

The naturally occurring peptide GHK-Cu (GHK from glycyl-L-histidyl-L-lysine bound to a copper ion), which affects 31.2% of the human genes by either activating or deactivating them (based on a criterion of a reduction or increment in gene activity of more than 50%), meaning that it works by inducing epigenetic alterations in the cells

10.1007/s00210-024-03485-x 48 WellmanA

Several factors influence how well your skin responds to peptide therapy after weight loss