In addition to this endocrine action, the local inhibitory effect of DPP-4 inhibitors on GLP-1 degradation in the intestinal mucosa may contribute to favorable metabolic regulation by stimulating the autonomic afferent nervous system (10, 19)
GLP-1 drugs (e.g., Ozempic, Wegovy, Trulicity) mimic this hormone to treat type 2 diabetes and obesity
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Worldwide inertia to the use of cardiorenal protective glucose-lowering drugs (SGLT2i and GLP-1 RA) in high-risk patients with type 2 diabetes
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Any personal protocol should come from the prescribing provider