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Polystyrene nanoplastics induce intestinal and hepatic inflammation through activation of NF-B/NLRP3 pathways and related gut-liver axis in mice

A multidisciplinary expert consensus published in Frontiers in Endocrinology recommends starting with osmotic laxatives (MiraLAX or magnesium) and only escalating to stimulant laxatives if osmotic options prove insufficient after 2-3 weeks of consistent use