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doi: 10.1017/s0029665100000847
In a 1-year phase II study, the daily dose was about 10% of the high-dose liraglutide, and the weight loss was about twice the original
Authors contributions Conceived and designed the experiments, supervision: HW ZL QY
As blood glucose levels drop, triglycerides in adipose tissue are hydrolyzed and free fatty acids (FFAs) are mobilized in the blood stream and become available for other tissues [1, 2]
Signs that insulin may be needed include persistently elevated blood sugar despite maximum GLP-1 doses, declining endogenous insulin production, and treatment plateaus that suggest the incretin-based approach has reached its limits
You can learn more about safety considerations in this IV therapy safety guide
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