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Loading phase: Initial protocols often use 2-2.5mg twice weekly for 4-6 weeks
This deep cellular hydration translates to plumper, more resilient skin that can better withstand environmental stressors
Retinoids have strong RCT evidence for collagen stimulation at 12 to 24 weeks, with FDA approval for photoaging indications
In laboratory research, DSIP is applied in studies examining hypothalamic signaling, EEG-defined sleep stages, and neurochemical regulation of sleep-wake cycles
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