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15 Injection site preparation & antisepsisBest-practice guidance on skin antisepsis and air-drying before subcutaneous injection

Most protocols recommend two to four weeks off after each four to eight week treatment cycle

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86,87 Modic change-like changes were also reported after perforation of the endplates in a pig model: oedema, fibrosis, and inflammatory cell infiltration into the bone marrow around the endplate defect were seen