Of particular interest, the discovery of GLP-1 receptor expression in the myocardium and in the vascular endothelium suggested possible roles of GLP-1 in the cardiovascular system and multiple preclinical studies support cardioprotective effects of native GLP-1 (Fig
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Characteristic symptoms include sudden-onset pain in the right upper quadrant or epigastrium, pain radiating to the right shoulder, episodes lasting 30 minutes to several hours (often after fatty meals), and associated nausea and vomiting
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