Statements Author contributions SA: Conceptualization, Supervision, Visualization, Writing original draft, Writing review & editing
Tirzepatide, the active ingredient in Mounjaro (for type 2 diabetes), was in short supply throughout 2022 and 2023 due to surging demand and limited manufacturing capacity
Retatrutide occupies a gray zone: it's a novel investigational compound, not a shortage drug, so standard compounding pathways are more limited
One pilot study investigating a combination of glycine and N-acetylcysteine was shown to help older adults rather than younger ones, helping to reduce inflammation, glutathione deficiency, endothelial dysfunction, and 'multiple aging hallmarks'
Some healthcare providers may recommend a modified approach for specific patient populations
TB-500 in actin polymerization (= reorganization of the cellular skeleton) and mobilization of stem cells to the site of injury